Analytical Intelligence
Exploring the Evolution of the Analytical Function in an Era of Big Data, Modeling, and AI
8/11/2026 - August 12, 2026 ALL TIMES EDT
CHI's new Analytical Intelligence track offers a comprehensive view of how data-driven approaches are influencing modern analytical strategies. Sessions will cover the collection, management, and interpretation of complex datasets across instruments, modalities, and development stages, including the use of active learning for training data generation. The track will examine the impacts of predictive modeling on formulation design, stability assessment, and analytical target profile development, as well as its role in supporting process development, PAT systems, and CMC decision-making. Challenges and solutions related to digitization, integration of partnered assets, regulatory filings, and adaptation of experimentalists to new digital paradigms will be discussed, alongside tools for automated data integrity review and advanced visualization.
Preliminary Agenda

OPTIMIZING PREDICTIVE ANALYTICS

Multimodal ML Framework to Predict Antibody Viscosity

Photo of Krishna D. Bharadwaj Anapindi, PhD, Senior Scientist, Biology, Gilead Sciences Inc. , Senior Scientist , Biology , Gilead Sciences Inc
Krishna D. Bharadwaj Anapindi, PhD, Senior Scientist, Biology, Gilead Sciences Inc. , Senior Scientist , Biology , Gilead Sciences Inc

High-Throughput Surrogate for Viscosity and Aggregation

Photo of Pin-Kuang Lai, PhD, Assistant Professor, Chemical Engineering and Materials Science, Stevens Institute of Technology , Dr , Chemical Engineering and Materials Science , Stevens Institute of Technology
Pin-Kuang Lai, PhD, Assistant Professor, Chemical Engineering and Materials Science, Stevens Institute of Technology , Dr , Chemical Engineering and Materials Science , Stevens Institute of Technology

Accelerating Biologics Development with Predictive Stability Modeling

Photo of Dan (Cassie) Liu, Principal Statistician, Bristol Myers Squibb , Senior Principal Statistician , Bristol Myers Squibb Co
Dan (Cassie) Liu, Principal Statistician, Bristol Myers Squibb , Senior Principal Statistician , Bristol Myers Squibb Co

Implementing a Combined Wet Lab and Dry Lab Initiative to Optimize Developability Studies

Kedric Milholland, PhD, Senior Scientist, Biologics Drug Product Development, AbbVie Inc. , Sr Scientist , Biologics Drug Product Dev , AbbVie Inc

Unlocking the Capabilities of Microfluidic Electrophoresis for the Development of Protein-Based Therapeutics Using Predictive Analytics

Photo of Jenna Rutberg, Researcher, Biomedical Engineering, Brown University , Graduate Student , Biomedical Engineering Tripathi Lab , Brown Univ
Jenna Rutberg, Researcher, Biomedical Engineering, Brown University , Graduate Student , Biomedical Engineering Tripathi Lab , Brown Univ

Use of Bayesian Optimization for Analytical Method Development

Rose Yin, PhD, Senior Scientist, Merck , Senior Scientist , Merck

EXPANDING DATA CAPTURE AND ANALYSIS

Presentation to be Announced

Photo of Sukru Kaymakcalan, Director, R&D Information Research, AbbVie, Inc. , Dir R&D Information Research , R&D Information Research , Abbvie Bioresearch Center
Sukru Kaymakcalan, Director, R&D Information Research, AbbVie, Inc. , Dir R&D Information Research , R&D Information Research , Abbvie Bioresearch Center

DIGITAL TOOLS FOR ANALYSIS AND INTERPRETATION OF COMPLEX RESULTS

Pattern Recognition across Methods, Modalities, Stages, and Time

Photo of Michael Butler, PhD, Principal Investigator, Cell Technology, National Institute for Bioprocessing Research & Training (NIBRT) , Principal Investigator/ Professor , Cell Technology , Natl Institute for Bioprocessing Research & Training NIBRT
Michael Butler, PhD, Principal Investigator, Cell Technology, National Institute for Bioprocessing Research & Training (NIBRT) , Principal Investigator/ Professor , Cell Technology , Natl Institute for Bioprocessing Research & Training NIBRT

Advances in Analytical Support of Process Development, CQA Identification, and Process Control Systems

Photo of Francesco Destro, PhD, Principal Engineer, BioCurie; Researcher, Chemical Engineering, Center for Biomedical Innovation, Massachusetts Institute of Technology , Postdoctoral Associate , Chemical Engineering , MIT
Francesco Destro, PhD, Principal Engineer, BioCurie; Researcher, Chemical Engineering, Center for Biomedical Innovation, Massachusetts Institute of Technology , Postdoctoral Associate , Chemical Engineering , MIT

PROBLEMS AND SOLUTIONS

In silico Models to Speed-Up and De-Risk Biologics Developability and Formulation Development

Photo of Andrea Arsiccio, PhD, Senior Scientist & Team Lead, In Silico, Coriolis Pharma Research GmbH , Sr Scientist & Team Lead , In Silico , Coriolis Pharma Research GmbH
Andrea Arsiccio, PhD, Senior Scientist & Team Lead, In Silico, Coriolis Pharma Research GmbH , Sr Scientist & Team Lead , In Silico , Coriolis Pharma Research GmbH

Cytokine Bioassays to AI Prediction: Assessing Immunogenicity of mAb Charge Variants and Aggregates

Photo of Rozaleen Dash, PhD, Senior Research Scientist, DBT Center of Excellence for Biopharmaceutical Technology, Indian Institute of Technology , Senior Research Scientist , Chemical Engineering , Indian Institute of Technology Bombay
Rozaleen Dash, PhD, Senior Research Scientist, DBT Center of Excellence for Biopharmaceutical Technology, Indian Institute of Technology , Senior Research Scientist , Chemical Engineering , Indian Institute of Technology Bombay

Monoclonal antibody heterogeneities, including charge variants and aggregates, can influence immunogenicity through altered cytokine responses. We combined human PBMC-based cytokine release assays with mechanistic modeling and deep neural network regression to evaluate immunogenic risk. Trastuzumab charge variants and stress-induced aggregates of rituximab and infliximab displayed distinct cytokine profiles linked to functional differences. The integrated experimental–computational framework successfully predicted cytokine dynamics, offering a translational approach to assess and mitigate immunogenicity risks during biotherapeutic development.

Single-Cell RNA Sequencing Identifies Cellular Heterogeneity Impacting Product Formation in CHO Perfusion Culture

Sean Engels, PhD, Senior Scientist, Process Research and Development Enabling Technologies, Merck , Sr Scientist , Process R&D Enabling Technologies , Merck & Co

Strategies for Adapting Experimentalists to Digital Tools and New R&D Paradigms

Photo of Bo Zhai, PhD, Principal Scientist, Analytical Method Development, Janssen , Sr Scientist , Mass Spectrometry , Janssen R&D LLC
Bo Zhai, PhD, Principal Scientist, Analytical Method Development, Janssen , Sr Scientist , Mass Spectrometry , Janssen R&D LLC

For more details on the conference, please contact:

Kent Simmons

Senior Conference Director

Cambridge Healthtech Institute

Phone: (+1) 207-329-2964

Email: ksimmons@healthtech.com

 

For sponsorship information, please contact:

 

Companies A-K

Phillip Zakim-Yacouby

Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-247-1815

Email: philzy@cambridgeinnovationinstitute.com

 

Companies L-Z

Aimee Croke

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-292-0777

Email: acroke@cambridgeinnovationinstitute.com