2024 Poster Presentations
Preliminary List as of July 2
4basebio Discovery Ltd.
Production of AAV Vectors Using Synthetic, Enzymatically Produced Linear DNA
AbbVie Bioresearch Center, Inc.
Mass Spectrometry Characterization of Adeno-Associated Virus 9 (AAV9)
Advanced Cell & Gene Therapy, LLC
Effective CMC Due Diligence for Cell and Gene Therapy Products and Technology
Advanced Instruments, Inc.
Osmolality Testing of Viscous Formulations Using Freezing Point Depression
Amgen, Inc.
Development of an Improved Upstream Process to Accelerate Multi-Modality Drug Discovery Pipeline
Aragen Biologics Private Limited
Enhancing Platform Process Using Membrane Chromatography (Affinity/Protein-A, Using Sartobind Rapid A) for FIH Molecules with Focus on Optimizing Cost and Accelerating Timelines
Arcturus Therapeutics
High-Throughput Automated IVT with Liquid Handler
Avantor, Inc.
A Novel Cell Lysis Solution with Advantageous Use Characteristics for rAAV Manufacturing that Can Lead to Greater Downstream Recovery by Minimizing Upstream Loss
BASF Corporation
Enhanced CAR-T Transduction with Lentiviral Vector (LV) in Medium Supplemented with Poloxamers P 188 and P 338
BASF Corporation
Evaluation of Foam Stability and Shear Protection of Kolliphor® P188 Bio and Kolliphor® P188 Cell Culture
BASF Corporation
Impact of Poloxamer 188 on Membrane Rigidity and Lipid Content of CHO-S cells
BASF Corporation
Investigating Poloxamer 188 and Cell Membrane Interaction in CHO-S Cells Using Microscopy
Beam Therapeutics
Multifaceted Application of the Cue Cell Processing System for Automated and Closed Manufacturing of CD34+ Hematopoietic Stem and Progenitor Cells (HSPCs)
Bio-Rad Laboratories
Development of an Ion Exchange Purification Process for Lentiviral Vectors
Bio-Rad Laboratories
Implementing Sustainability in mAb Purification Workflows
Bio-Rad Laboratories
Separation of Bispecific-Antibody Related Impurities with Mixed-Mode Chromatography
Boston Institute of Biotechnology
A Comparative Study to Evaluate Different Analytical Methods Used to Quantify a Fusion Protein and Two Types of IgG Molecules Produced in CHO Cell Line
Boston Institute of Biotechnology
An Assessment of Eco-Friendly Surfactants as Replacements for Triton™ X-100 During Cell Lysis, and Their Impact on the Primary Capture of a Therapeutic Protein
Chugai Pharmaceutical Co., Ltd.
Unraveling Differences in Antibody Production Between Manufacturing Sites Using Omics Analysis
c-LEcta GmbH
How to Compare the Technical Performance of S. marcescens endonucleases such as DENARASE® & Benzonase®?
CYTENA GmbH
An Optimized and Validated Workflow for Developing Stable Producer Cell Lines with >99.99% Assurance of Clonality and High Clone Recovery
ElevateBio
Design and Production of Circular RNAs (circRNAs) with Validated Functional Activity in Cell Models.
ElevateBio
Evaluation of Alternative Process Cell Lysis Reagents as Replacements for Triton™ X-100 for AAV Production
ElevateBio
Rapid Development of Ion Exchange Chromatography for Full/Empty Separation in Adeno-Associated Virus Serotype 5
Evitria AG
In Silico Optimization of Polishing of Bispecific Antibodies Using Ion-Exchange Chromatography
Forge Biologics
Adaptive Downstream Platform Process for Accelerated rAAV Therapeutic Development: Integrating Serotype-Specific Optimization
Gachon University
Patient-Derived Tumor Spheroid-Induced Angiogenesis Preclinical Platform
Genedata AG
Automated and Robust Identification of Scrambled Disulfide Bonds in Biotherapeutics
Genedata AG
End-To-End Software Platform for Streamlined LC/MS-Based Multi-Attribute Method (MAM) Implementation
Genevoyager, Inc.
Introduction to Genevoyager's One-Bac 4.0 System: Addressing the Bottlenecks and Challenges of Adeno-Associated Virus (AAV) Manufacturing
Gilead Sciences
Enabling Intravenous Co-Administration of Two Monoclonal Antibodies Enhancing Patient Convenience
Gyros Protein Technologies
High-Throughput, Automated Analysis of Process Related Impurities Accelerates Downstream Process Development of AAV Based Gene Therapies
Heriot-Watt University
The Design and Manufacture of Massively Scalable Inertial Focusing Prototype Microfluidic Devices
Intellia Therapeutics, Inc.
Salt Addition Impacts Recombinant AAV Particle Distribution in Cell Culture
InVitria
Cryoprotectant Additives Including rHSA Improve iNK and iT Cell Health and Viability During Cryopreservation
Isolere Bio
IsoTags - Novel and Effective Tools in Biotherapeutic Purification Arsenal
Lonza
Capture Step Intensification: Evaluation of Technology for Range of Titre and Scale of Operation
Lonza
In Silico Tool: Integrated Downstream Processing Platform for Monoclonal Antibodies Production
Lonza
RT-MALS Assisted Purification of Adeno-Associated Viruses During Early Process Development
Mediphage Bioceuticals, Inc.
Ministring DNA ( msDNA™ ): Maximizing Quality of Novel DNA Vectors
Merck & Co., Inc.
Evaluation of a High Throughput Scale Down Model for UFDF Operation
Merck & Co., Inc.
PAT for Flocculation Across Scales
Mettler Toledo GmbH
Development of a Dissolved CO2 Sensor in True Single-Use Format
MilliporeSigma
Characterization of Adeno-Associated Viral Vectors by SEC coupled with Light Scattering and UV Detection
MilliporeSigma
Optimizing Transfections for Increased AAV Titers and Effective Media Evaluations
MilliporeSigma
Optimizing Virus Filtration in Continuous Processing with Asymmetric Serial Filtration at High Membrane Area Ratio
Milliporesigma
Unlocking the High-Seed Fed-Batch Approach with Cellvento® ModiFeed Prime
National Institute of Advanced Industrial Science and Technology
A New Method to Produce Genome-Free-HSV Particle Vector
Navigo Proteins GmbH
Overcoming Challenges in Ferritin Extraction from Blood Plasma: Precise Affinity Chromatography Solutions
Nitto Avecia Pharma Services
Analysis of the Oxidation Status of the N-Glycan Species in a Humanized Monoclonal Antibody by QTOF Mass Spectrometry
Novoprotein Scientific, Inc.
A T7 RNA Polymerase Mutant that Can Significantly Reduce dsRNA Impurities
Panome Bio
Untargeted Metabolomic Profiling Reveals Process Optimization Strategies in a Mock Bioreactor
Prime Medicine, Inc.
High-Throughput Activity Assay for Prime Editor mRNA
ProteinSimple, A Bio-Techne Brand
Fractionation of Bispecific Antibody Charge Variants by MauriceFlex™ and their Identification by Mass Spectrometry
Repligen Corporation
Viral-Vector Therapies at Manufacturing Scale: Current Challenges and Future Opportunities
Revvity, Inc.
Addressing the HEK293 Host Cell Protein Monitoring Challenges for Viral Vector Gene Therapy Manufacturing
Sanofi
Efficiently Developing a Commercial-Scale Manufacturing Process for AAV Vector Gene Therapy
Sanofi
Selective Generation of mAb Degradants via Guided Modulation of Low pH Stress Conditions
Sanofi
Targeted Dual Selection to Optimize Transposon Stable Pool Generation of Multi-Specifics in Large Molecules Research
Sarepta Therapeutics
Enhancing rAAV Genome Integrity Through Process Development Optimization
Sartorius BIA Separations
Monolithic Columns Enable Streamlined Downstream Processing and Analytics of Lipid Nanoparticles
Sartorius Stedim Biotech GmbH
De-Bottlenecking the UF/DF Steps: Enhancing Recovery and Efficiency in a Continuous Downstream Process
SCIEX
Charge Variant Identification and Localization of Post-Translational Modifications with Integrated icIEF-UV/MS
SGS Canada Inc
Differential Scanning Fluorimetry for Assessing Thermal Stability of Protein Biologics
Slingshot Biosciences
Enhancing Immunophenotyping Standardization with Quantitative BCMA or CD19 Decorated Hydrogels
Slingshot Biosciences
Hydrogels Mimicking T, B, and NK Cells for Quality Assurance in Cell Therapy Development
Solventum
An Investigative Case Study of the Removal of Host Cell DNA from HEK Detergent Lysates using 3M™ Harvest RC Chromatographic Clarifier
Solventum
Fiber Chromatographic Clarification: Enhancing Rapid Cycling Protein A Chromatography Performance
Spark Therapeutics
Scalable Upstream Design: Robustness and Reproduceable Suspension Production from Benchtop to 500L STR Scale
Spark Therapeutics
The Optimization of Nuclease Application in AAV-Based Gene Therapy Manufacturing
Sphere Fluidics Ltd.
Picodroplets for Biologics Discovery and Cell Line Development: Accelerating the Discovery and Development Process
Spheryx, Inc.
Monitoring Polysorbate 80 Degradation as a Function of pH using Total Holographic Characterization
Sunresin New Materials Co., Ltd.
Exceptional High Alkaline Stability Combined with High Dynamic Binding Capacity for Scalable and Cost-Effective mAb Purification with New rProtein A Agarose Resin
Teva Pharmaceuticals
Impacts of Amino Acids in Formulation on Imaged Capillary Isoelectric Focusing (icIEF)
Thermo Fisher Scientific
Accelerating Antibody Drug Development with Subdomain-Specific Affinity Chromatography
Thermo Fisher Scientific
Customization of Gibco™ CHO Panel Formulations Produced by Gibco™ Rapid Prototyping™ Facility (GRP) Lead to Increase in Productivity for Two CHO Cell Lines with CHO-K1 and DG44 Lineages
Thermo Fisher Scientific
Enhancing Protein Titer in CHO Cells with a Novel Protein-Free Two-Part Feed System
Thermo Fisher Scientific
Moving Forward: Rapid Detection of Bacteria and Fungi in Cell Therapy Products
Tozaro Ltd.
Novel Pseudo-Affinity Reagents for Lentivirus Analytics and Affinity Chromatography
Ultragenyx Pharmaceutical, Inc.
An Accelerated Approach to Upstream Process Characterization of an AAV-Based Gene Therapy for Sanfilippo Syndrome (MPSIIIA)
Ultragenyx Pharmaceutical, Inc.
Development of a High Throughput Purification Method to Support Late-Stage Development and Process Characterization of an Accelerated Clinical Program
University Jaume I
Characterizing the mRNA Expression Profile Associated with Accelerated Aging for the Development of Anti-Aging Biotherapeutics
University of Groningen
Unlocking Optimal Conditions for HEK293T Cell Expansion Using SCINUS Bioreactor Technology
University of Valencia
Host Characteristics and Changes in Omics Biomarkers Following Vaccination with Distinct COVID-19 Vaccines in an Elderly Mediterranean Population
W. L. Gore & Associates, Inc.
Building a Fully Single-Use Process: High Productivity Protein A Membrane Devices that Complement Disposable Upstream Technology
WEJ Cell & Gene Therapy Consulting Services, LLC
Knowing the End of the Story While Writing the Beginning: Development of an Effective and Durable Cell/Gene Therapy CMC
Wyatt Technology Corporation
Advances in Downstream PAT for Biologics, Vaccines and Gene Vectors
Zoetis
Extended Cycle Lifetime Study of Fibro PrismA Rapid Cycling Chromatography Using Cytiva’s HiTrap and HiScreen Devices