Cambridge Healthtech Institute’s 17th Annual

Cell Culture & Cell Line Optimization

August 16-17, 2021


Biopharmaceutical companies today are challenged to develop high-producing cell lines as quickly as possible. Advances in cell engineering, improved culture conditions, and enhanced culture analysis are giving rise to new techniques and optimized cell environments to maximize cell growth and metabolism. Recent advances in proteomics, transcriptomics, CRISPR, digitalization and automation, have enabled deeper understanding of cell culture and cell line processes and expedited cell line development for production of high quality biologics. CHI's 17th Annual Cell Culture & Cell Line Optimization conference provides an open forum for cell culture and cell line development scientists to discuss their latest technologies and approaches to improve titer, enhance stability and reduce cost.


Coverage will include, but is not limited to:


  • Systems and synthetic biology to improve upstream biologics production
  • Transforming cell culture and cell line development with OMICS approach – proteomics and transcriptomics
  • Advances in molecular biology and genome editing tools
  • Cell culture control and analysis – modeling, PAT, DOE integration for faster process understanding and process control to achieve desired product quality attributes
  • Beyond CHO – alternative host systems, insect cell platforms, cell-free synthesis, etc.
  • Intensified/integrated continuous perfusion processes for CHO and HEK293 cells
  • Engineering CHO cells for production of DTE proteins
  • Expediting cell line development for production of high quality biologics
  • COVID-19 antibody cell line development
  • Novel approaches and technologies to deliver engineered/selected cells
  • CRISPR technology for cell line editing
  • Establishing recombinant cell lines with improved performance
  • Cell line design, screening and scalability strategies to optimize expression for antibodies, BsAbs, exosomes, nanoparticles, nucleic acids
  • Automation, digitalization and data integration – high-throughput screening, machine learning for single-cell imaging, PAT and feedback control


If you would like to submit a proposal to give a presentation at this meeting, please click here.


The deadline for priority consideration is January 29, 2021.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


For more details on the conference, please contact:

Mimi Langley

Senior Conference Director

Cambridge Healthtech Institute

Phone: (+1) 781-972-5439



For partnering and sponsorship information, please contact:

Companies A-K

Sherry Johnson

Senior Manager, Business Development

Cambridge Healthtech Institute

Phone: (+1) 781-972-1359



Companies L-Z

Jon Stroup

Senior Manager, Business Development

Cambridge Healthtech Institute

Phone: (+1) 781-972-5483


Speaker Proposal