Cambridge Healthtech Institute’s 6th Annual

Advances in Purification & Recovery

Optimizing and intensifying downstream processes

August 26-27, 2020

 

New and emerging molecules coming down the pipeline bring new sets of challenges to the downstream team. Downstream scientists are increasingly looking to disruptive technologies, including process intensification and optimization, automation, scale-down modeling and high-throughput processes to meet the challenges of higher upstream titers and complex molecules while improving product yield and reducing cost. CHI’s 6th Annual Advances in Purification & Recovery invites scientists to discuss their challenges in purification of new modalities such as viral vectors, exosomes, bispecifics and ADCs etc., and to share their latest development in next-generation processing by leveraging novel technologies, process intensification and digitalization.

Preliminary Agenda

PURIFICATION OF NOVEL BIOTHERAPEUTICS

Raising the Bar on the Purity of Exosome Therapeutics

Andrew Wood, MS, Senior Scientist, CMC, Codiak Biosciences

Integration of Synthetic Chemistry, Small Molecules and Biologics Development and Manufacturing Strategies to Deliver Novel Antibody Drug Conjugates

Engin Arturk, PhD, Director, CMC Process Engineering & Bioconjugation, Mersana Therapeutics

Purification of Virus/Viral Vectors for Gene Therapy

Srinivas Chollangi, PhD, Associate Director, Voyager Therapeutics

VIRUS INACTIVATION & NANOFILTRATION

Challenges and Approaches to Virus Inactivation and Nanofiltration of Hydrophobic Monoclonal Antibodies

Green Guihang Zhang, PhD, Director, Purification Process Sciences, Incyte Corporation

TECHNOLOGY COMPARISON AND ADVANCES IN PROTEIN CAPTURE

Comparison of Throughput and Performance between Bead, Membrane, and Nanofiber-Based Chromatography for Protein A Capture

Prashant Ganji, Senior Scientist, Purification Process Development, Pfizer Inc.

Primary Recovery: Shedding Some Light on a Grey Zone

Elie El Kawkabani, MSc, Scientist, Upstream Process Sciences, UCB

ZCa – A Calcium-Dependent Protein A Domain for Mild Antibody Purification

Sara Kanje, PhD, Researcher, Protein Science, Royal Institute of Technology (KTH)

IMPROVING DOWNSTREAM PRODUCTIVITY, FLEXIBILITY AND REDUCING COST

A Self-Cleaving Tag Platform to Support Basic Discovery through Full-Scale Manufacturing

David Wood, PhD, Professor, Chemical and Biomolecular Engineering, Ohio State University

Super-Batch Chromatography for Clinical Manufacturing

Dharmesh Kanani, PhD, Associate Director, R&D Unit, Teva Pharmaceuticals

Talk Title to be Announced

Soumya Mohanan Krishanthu, Senior Associate Scientist, Janssen Pharmaceutical companies of Johnson & Johnson




For more details on the conference, please contact:
Mimi Langley
Senior Conference Director
Cambridge Healthtech Institute

Phone: (+1) 781-972-5439
Email: mlangley@healthtech.com

 

For partnering and sponsorship information, please contact:

Companies A-K
Sherry Johnson
Senior Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-1359
Email: sjohnson@healthtech.com

Companies L-Z
Carolyn Cooke
Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-5412
Email: ccooke@healthtech.com



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