Cambridge Healthtech Institute’s 11th Annual

Optimizing Cell Line Development

Enhancing Expression

August  15-16 , 2019

Cell Line Development has reached a new plateau influenced by genomic research and insights, along with emerging technologies that are pushing cell engineering into an uncharted future. The “Optimizing Cell Line Development” conference brings together experts who are forging this new era. They will share how to best optimize codons, construct vectors, and how to select and engineer clones and host systems, while maintaining stability and consistency. The conference will also focus on genomic research for CHO and other systems, as well as glycoengineering, systems biology, assays, and pathway delineation.  In addition, challenges for introducing new technologies will be discussed, along with an overview of industrial trends and regulatory perspectives.

Topics will include, but are not limited to:

  • Gene expression / expression levels
  • Genomic research
  • Glycoengineering
  • Trends in industrial cell line development, such as CRISPR
  • Codon optimization
  • Vector construction
  • Clone selection & optimization
  • Host system selection & use
  • Cell line selection
  • Cell line attributes
  • High producer cell lines / industrial use
  • Synthetic Biology
  • Regulatory perspectives on new technologies
  • Systems Biology
  • Metabolomics
  • Hurdles for introducing new technologies
  • Sequencing the CHO genome
  • Transcriptomic data
  • Predictive modeling
  • Identifying the best hosts
  • Understanding hosts to control phenotypes
  • Engineering hosts
  • Designing a cell line for biosimilars
  • Arrays / Microarrays
  • Process conditions & robustness
  • Developing new cell lines
  • Cell growth
  • Stability
  • Productivity
  • Reproducibility
  • Quality
  • Scalability
  • Cell line serviceability through late-stage product development
  • Protocols & Case Studies

If you would like to submit a proposal to give a presentation at this meeting, please click here.

The deadline for priority consideration is February 11, 2019.

All proposals are subject to review by session chairmen and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

For more details on the conference, please contact:
Mary Ruberry
Senior Conference Director
Cambridge Healthtech Institute
Phone: 781-972-5421

For partnering and sponsorship information, please contact:

Companies A-K
Sherry Johnson
Business Development Manager
Cambridge Healthtech Institute
Phone: 781-972-1359  

Companies L-Z
Carolyn Benton
Business Development Manager
Cambridge Healthtech Institute
Phone: 781-972-5412