Cambridge Healthtech Institute’s 4th Annual

Advances in Purification & Recovery

Optimizing Existing Processes and Industrializing Next-Generation Products

August 15-16, 2018

Downstream yields continue to lag behind upstream titers, urging biopharma manufacturers to go after automation, high throughput processes and continuous manufacturing to meet upstream titers.

Meanwhile, new and emerging products are coming down the pipeline, giving rise to more anxiety among biopharm manufacturers to find ways to industrialize their processes for these non-platform molecules.

At CHI’s 4th Annual Advances in Purification & Recovery conference, we invite scientists to share their pursuit of new technologies and approaches to enhance productivity and reduce bottlenecks, and to highlight strategies and best practices in downstream purification of novel, non-platform products from bispecific antibodies, cell and gene therapies, to viral vaccines and microbial-expressed proteins.

Topics will include, but are not limited to:

  • Non-Platform Downstream Processes for Emerging Products 
    • Bispecific antibodies
    • Cell and gene therapies
    • Microbial production and difficult-to-express proteins
    • Viral vaccines, VLPs
    • ADCs and other conjugated therapies
    • Enzymes and complex proteins
    • Nanoparticles
  • New Advances, Technologies and Approaches  
    • New affinity resins/technologies with improved binding strength
    • Hydrogel membrane technology
    • Acoustic Wave Separation
    • Flow through vs Bind-and-Elute
    • Novel harvest methods for high cell density cultures
    • Better management of buffer preparation
    • Single-Use tangential flow filtration for virus inactivation
    • Continuous purification
      • Multi-column capture/column switching for continuous processes
      • Process intensification   
  • Automation, Predictive Modeling and High Throughput Processes to Improve Efficiencies and Reduce Bottlenecks 
    • Automating platform technologies
    • Integrating robotics, automation and high throughput process development
    • High throughput polishing methods to improve antibody quality
    • QbD in downstream processing
    • Predictive modeling – mimicking large scale production using scale down models

If you would like to submit a proposal to give a presentation at this meeting, please click here.

The deadline for priority consideration is February 2, 2018.

All proposals are subject to review by session chairmen and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per CHI policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

For more details on the conference, please contact:

Mimi Langley

Senior Conference Director

Cambridge Healthtech Institute

Phone: 781-972-5439


For partnering and sponsorship information, please contact:

Companies A-K

Sherry Johnson

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: 781-972-1359


Companies L-Z

Carolyn Benton

Business Development Manager

Cambridge Healthtech Institute

Phone: 781-972-5412