Cambridge Healthtech Institute’s 3rd Annual

Host Cell Proteins

Detection, Analayis and Control

August 13-14, 2018


A critical part of bioprocessing is the control of process-related impurities such as host cell proteins (HCPs), which co-purify with the drug substance and can cause adverse effects such as immunogenicity. Analytical methods are available but coverage and specificity is limited. Moreover, the emergence of new expression systems, new products and new techniques such as mass spectrometry has further compounded these limitations with regulators now pressing companies for more HCP data.

CHI’s Host Cell Proteins conference brings together industry leaders to discuss critical HCP topics such as: risk assessment and control strategies, HCP characterization, assay coverage, critical reagents and platforming, plus questions relating to biosimilars, in-process testing and the latest data supporting the link between HCPs and immunogenicity.

Cover will include, but is not limited to:

  • Regulatory considerations for HCPs – industry and regulatory experience
  • Clinical relevance of HCPs
  • Risk Assessment strategies across companies
  • Control strategies
  • Process development strategies to control HCPs
  • In-Process testing
  • Integrating HCP testing into a platform
  • HCP characterization
  • Mass spectrometry
  • Industry application
  • Improving label-free quantification
  • Assay development
  • Assay coverage
  • Critical reagents
  • When to change assays
  • Criteria for bridging
  • HCPs, biosimilars and comparability testing
  • New immunoassay technologies - α-LISA, HTRF, MSD, Gyrolab

If you would like to submit a proposal to give a presentation at this meeting, please click here.

The deadline for priority consideration is Friday, February 2.

All proposals are subject to review by session chairmen and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

For more details on the conference, please contact:
Daniel Barry

Senior Conference Director

Cambridge Healthtech Institute

Phone: 781-247-6266
Email: dbarry@healthtech.com

For partnering and sponsorship information, please contact:

Companies A-K

Sherry Johnson

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: 781-972-1359
Email: sjohnson@healthtech.com

Companies L-Z

Carolyn Benton

Business Development Manager

Cambridge Healthtech Institute

Phone: 781-972-5412
Email: cbenton@healthtech.com