2015 BPD Header

Cambridge Healthtech Institute’s 2nd Annual
Advances in Purification Technologies
Novel Advances and Continuing Improvements for Higher Downstream Productivity and Purity
August 6-7, 2015
Part of CHI's 7th Annual The Bioprocessing Summit

August 3-7, 2015 | Westin Copley Place Hotel | Boston, Massachusetts


The downstream processing field is experiencing a resurgence of vitality and innovation. Driven partly by the quest for higher titer and higher throughput for existing mAb processes and partly by the next generation, non-monoclonal molecules coming down the pipeline, we are seeing exciting new developments in each step of downstream processing - from capture to purification to polishing. New, higher capacity and multi-modal ligands that can eliminate aggregates; advances in filters and flocculants for better binding and getting rid of impurities; process improvements from 3 column to 2 columns and the promise of continuous purification technologies - all these are testaments to the exciting innovations that aim to deliver higher purity, higher titer and higher throughput.

CHI’s Second Annual Advances in Purification Technologies will invite scientists and engineers to share their experiences, trials and results with these new technologies and continuing improvements, where they have encountered challenges, and what pitfalls to avoid.


Preliminary Agenda 


ADVANCES IN CHROMATOGRAPHY

Development of Robust Impurity Clearance Methods Using Chromatographic and Non-Chromatographic Techniques

Srinivas Chollangi, Ph.D., Scientist II, Biologics Process Development, Bristol-Myers Squibb


ADVANCES IN NON-CHROMATOGRAPHIC PURIFICATION

How to Scale Up Precipitation of Recombinant Antibodies

Alois Jungbauer, Professor Department of Biotechnology, BOKU and Head of Bioprocess Engineering, Austrian Centre of Industrial Biotechnology

Fatty Acid Reduction of Contaminants from Mammalian Cell Culture Harvests

Wei Zhang, Ph.D., Research Scientist, Downstream Processing, Bioprocessing Technology Institute, Singapore

Single Step Purification of Biotherapeutic Proteins in a Highly Simplified Process Using an Optimized, Proprietary Fragment Complementation System

David O’Connell, Ph.D., Lecturer, Director, MSc Programmes, Biotechnology, School of Biomolecular & Biomedical Research, University College Dublin


PURIFICATION OF COMPLEX/NEXT GENERATION MOLECULES & PRODUCTS

Modular Approaches to Express and Purify Complex Therapeutic (Fusion) Proteins

Stefan R. Schmidt, Ph.D., MBA, Vice President, DSP Production, Rentschler Biotechnologie GmbH

Membrane Proteins: From Lab-Scale toward Large-Scale Production

Julie Bomholt, Ph.D., Protein Specialist, Research & Development, Aquaporin A/S

Antigen Purification for Biologics Projects

Medha J. Tomlinson, Ph.D., Senior Scientist III, Global Biologics – Protein Sciences, Abbvie Bioresearch Center


HIGH TITER AND HIGH THROUGHPUT PURIFICATION

Miniaturized and Automated Inclusion Body Processing – from Homogenization to Purification

Cornelia Walther, Ph.D., University of Natural Resources & Life Sciences

High Pressure Refolding of Proteins at High Concentrations

Linda Gombos, Ph.D., Biopharmaceuticals Process Science, Downstream Processing, Boehringer-Ingelheim RCV GmbH & Co., KG


SCALING DOWN PROCESSES

Scaled-Down Processes as Predictive Models for Larger Scale Manufacturing (tentative title)

Omkar Joshi, Ph.D., Laboratory Head, Downstream Development, Bayer Pharma AG




For more details on the conference,
please contact:

Mimi Langley
Sr. Conference Director
Phone: (+1) 816-471-0701
Email: mlangley@healthtech.com 

For exhibit & sponsorship opportunities, please contact: 

Companies A-K:
Elizabeth Lemelin
Business Development Manager
Phone: 781-972-1342
Email: elemelin@healthtech.com 

Companies L-Z:
Sherry Johnson
Business Development Manager
Phone: 781-972-1359
Email: sjohnson@healthtech.com