Cambridge Healthtech Institute’s 3rd Annual
Advances in Purification Technologies
Part of CHI's Ninth Annual The Bioprocessing Summit
August 23 - 24, 2017 | Westin Copley Place | Boston, MA

Downstream processing is an area ripe for technology innovations. With higher upstream titers creating bottlenecks in downstream, and high cost of proteinA resins, the downstream steps are not only cumbersome, but also inefficient and costly. With single-use technologies and continuous processing making headways into downstream processing and offering cost-savings, higher productivity gains and faster turnarounds, companies are now looking for alternative technologies that can further revolutionize the downstream industry. These include alternatives to proteinA, alternatives to cell culture clarification, membrane filtration technologies, depth filtration, new adsorbents, novel precipitation and flocculation techniques, etc.

CHI’s 3rd Annual Advances in Purification Technologies invites scientists who are exploring these alternative techniques to share their experiences, discuss their goals and gains, as well as offer advice on challenges to overcome and pitfalls to avoid.

Preliminary Agenda

Protein Engineering and Evolving Demands in Protein Purification: A Critical Appraisal of Workflow Options in Downstream Processing

David O’Connell, Ph.D., Lecturer in Biotherapeutics, School of Biomolecular & Biomedical Science, University College Dublin


Downstream Processing Challenges of an E. Coli-Expressed Insulin-Like Peptide

Nina Madsen, MSc., Scientist, Downstream Process Development, Bristol Myers Squibb

Purification of Common Light Chain IgG-Like Bispecific Antibodies Using Highly Linear pH Gradients

Beth Sharkey, Associate Scientist, High Throughput Expression, Adimab, LLC.

Downstream Process Development of an in vivo Radiolabeled Diagnostic Expressed in E. Coli

Brian O’Mara, Ph.D., Senior Scientist, Biologics Process Development Group, Bristol Myers-Squibb


Efficient Devices for Process-Scale Chromatography

Raja Ghosh, Ph.D., Professor, Canada Research Chair in Bioseparations Engineering, Chemical Engineering, McMaster University

Advances and New Approaches in Affinity Chromatography

Krunal Mehta, Ph.D., Scientist, Amgen

Evaluation of Straight-Through Protein Chromatography to Enable Truly Continuous Bioprocessing

Stefano Menegatti, Ph.D., Assistant Professor, Department of Chemical and Biochemical Engineering, University of North Carolina

Use of Activated Carbon as an Adsorbent in the Polishing Step

Gerd Kern, Ph.D., Director, Chromatrography Media, Merck

Bioxcellence Tech Transfer Concept – An Insight in General Tech Transfer Approach Including BI´s Quality Culture Initiative

Daniel Kronberger, MSc., Head of Downstream Pilot, Process Sciences, Boehringer Ingelheim RCV GmbH & Co KG

For more details on the conference, please contact:
Mimi Langley
Senior Conference Director
Phone: 781-972-5439

For media partnership opportunities, please contact:
Kaushik Chaudhuri
Director of Product Marketing
Phone: 781-972-5419

For exhibit & sponsorship opportunities, please contact:

Companies A-K
Sherry Johnson
Business Development Manager
Phone: 781-972-1359

Companies L-Z
Carolyn Benton
Business Development Manager
Phone: 781-972-5412

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