Cambridge Healthtech Institute’s 4th Annual
High-Concentration Protein Formulations:
Formulation, Manufacturing, Analytics, High Viscosity, Aggregation, Devices and Delivery
August 5-6, 2015
Part of CHI's 7th Annual The Bioprocessing Summit
August 3-7, 2015 | Westin Copley Place Hotel | Boston, Massachusetts
At higher concentrations, proteins or antibodies exhibit characteristic problems including aggregation, precipitation, gelation, and increased viscosity. Development of these high-concentration protein formulations results in several manufacturing, stability, analytical, and delivery challenges. The popular High-Concentration Protein Formulations conference will feature informative, high quality case studies and successful strategies to overcome the problems you are facing with development and delivery of high-concentration formulations. We invite you to attend to learn from and network with the leading experts from around the world.
Protein-Protein Solvation in High-Concentration Solutions
Thomas Laue, Ph.D., Professor, Biochemistry and Molecular Biology; Director, Biomolecular Interaction Technologies Center (BITC), University of New Hampshire
Viscosity in High-Concentration Protein Formulations
Thomas Palm, Ph.D., Senior Research Investigator II, Drug Product Science and Technology, Bristol-Myers Squibb Co.
Cluster Formation in Dense Protein Solutions and Its Implications to Solution Viscosity
Yun Liu, Ph.D., Research Associate Professor/Instrument Scientist, Chemical & Bimolecular Engineering/Center for Neutron Research, University of Delaware/National Institute of Standards and Technology
HESylation® - A Versatile Polymer Modification Technology Enabling High-Concentration Protein Formulations
Thomas Hey, Ph.D., Director, Biochemistry, Innovation Center Complex Formulations, Fresenius Kabi Deutschland GmbH
Drug Product Design and High Concentration Formulation Development
Bruce Kerwin, Ph.D., Head, Drug Product Design, Just, Inc.
CMC Strategies on Scaling Up and Down for High-Concentration Protein formulations
Jamie Tsung, Ph.D., Principal Scientist, Momenta Pharmaceuticals, Inc.
Determination of Low Levels of Polysorbates in High Concentration Drug Substances and Drug Products
Shiranthi Jayawickreme, Ph.D., Associate Director, Analytical Development, Biogen Idec
Analytical Challenges with High-Concentration Protein Formulations
Michael S. Marlow, Ph.D., Senior Staff Scientist, Protein Biochemistry, Regeneron Pharmaceuticals, Inc.
Reconstitution of Highly Concentrated Protein Formulations
Bakul Bhatnagar, Ph.D., Principal Scientist, Formulation & Process Development, Pfizer, Inc.
Device & Formulation – Two Inseparable Aspects of a Successful Product
Jan Jezek, Ph.D., CSO, Development, Arecor Ltd.
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