Plenary Keynote Session
Wednesday, August 23 (4:45 - 6:00pm)
John Sterling, M.A., Editor-in-Chief,
Genetic Engineering & Biotechnology News
Protein Aggregation and Oxidation during Processing
Jean-René Authelin, Ph.D., Global Head, Pharmaceutical Engineering, Sanofi
Proteins are known to be sensitive to many stresses, including oxidation and shear stress, leading to potentially immunogenic aggregates. In this talk, we will present theoretical aspects together with real-life industrial examples illustrating the possible traps we may find in the fill & finish processing. We will, as well, propose the experiments that need to be performed in order to understand and predict the risk and the practical industrial solutions to implement solutions accordingly.
Videos from Past Plenary Keynote Sessions: