The Bioprocessing Summit
The Bioprocessing Summit

Cambridge Healthtech Institute’s 8th Annual
Optimizing Cell Line Development
Enhancing Expression
Part of CHI's 8th Annual The Bioprocessing Summit

August 18-19, 2016 | Westin Boston Waterfront | Boston, Massachusetts


The “Optimizing Cell Line Development” meeting brings together experts in cell line development and protein expression who share their real-world strategies for achieving cell lines that meet bottom-line goals faster and at lower expense. Their practical and detailed insights will illustrate how to best optimize codons, construct vectors, and how to select and engineer clones and host systems. Gaining a greater understanding of cells through sequencing and the omics sciences will also be addressed, including the CHO genome research, metabolomics, assays, and QPCR. In addition, challenges for introducing new technologies, such as in silico modeling, will be discussed, along with an overview of industrial trends and regulatory perspectives.

Topics may include, but are not limited to:

  • Codon optimization
  • Vector construction
  • Clone selection & optimization
  • Host system selection & use
  • Cell line selection
  • Cell line attributes
  • High producer cell lines/industrial use
  • Regulatory perspectives on new technologies
  • Omics technologies
  • Metabolomics
  • Hurdles for introducing new technologies
  • Sequencing the CHO genome
  • Gene expression/expression levels
  • Transcriptomic data
  • Predictive modeling
  • Identifying the best hosts
  • Understanding hosts to control phenotypes
  • Engineering hosts
  • Lactate metabolism
  • Designing a cell line for biosimilars
  • Arrays/Microarrays
  • QPCR
  • Process conditions
  • Process robustness
  • Cell growth
  • Stability
  • Productivity
  • Quality
  • Scalability
  • Cell line serviceability through late-stage product development
  • Trends in industrial cell line development
  • Protocols & Case Studies

Cell Line Development experts who wish to present their knowledge and expertise to their colleagues are asked to click here to submit an abstract. Remember to specify the conference that you are interested in, and please provide your full contact information.

Deadline for submission is February 15, 2016.


All proposals are subject to review by the Scientific Advisory Committee to ensure the highest quality of the conference program. Please note that due to limited speaking slots, preference is given to pharmaceutical and biotech companies, regulators and those from academia. Additionally, vendors/consultants who provide products and services to these biopharmaceutical companies are offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

For more details on the conference, please contact:

Mary Ruberry
Senior Conference Director
Cambridge Healthtech Institute
Phone: 781-972-5421
E: mruberry@healthtech.com

For exhibit & sponsorship opportunities, please contact:

Companies A-K

Sherry Johnson
Business Development Manager
781-972-1359 | sjohnson@healthtech.com

Companies L-Z

Carolyn Benton
Business Development Manager
781-972-5412 | cbenton@healthtech.com

For media partnership opportunities, please contact:

Kaushik Chaudhuri
Director of Product Marketing
Phone: 781-972-5419
Email: kchaudhuri@healthtech.com